Preferences and Practices of Face Mask to Halt the Spread of COVID-19: A Multi-Country Research on the New Normal

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Neurological and Urological Malformations in Infant of Diabetic Mother at Tertiary Care Hospital; a Single Center Experience

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Adermatoglyphia (Loss of Fingerprints) in Young Female Patient Having the Conditions of Hyperhidrosis and Atopic Dermatitis

This is a case of Adermatoglyphia or simply a loss of fingerprints in a young female patient in her 20s having a condition of hyperhidrosis and atopic dermatitis. At a young age, this condition can be very frustrating and give the patient a red flag in his/her carrier and during international travel. The patient faces problems in unlocking smartphones and electronic devices. The patient has to keep a medical certificate from a certified Dermatologist all the time for proof of this condition. Adermatoglyphia is not recognized as a problem in society and law enforcement agencies are not aware of this condition in detail, all over the world

Prognostic Factors for Pulmonary Metastasectomy in Soft Tissue Sarcoma: An Integrative Review

The lung is one of the most common sites of metastasis from soft tissue sarcoma (STS). In the absence of a randomized control trial, pulmonary metastasectomy is commonly performed in an effort to improve survival. However, data from retrospective analysis and case series remain subject to selection bias. The aim of this study was to review the published data, especially to identify prognostic factors, to inform future clinical practice in the field of pulmonary metastasectomy for metastatic soft tissue sarcoma. We searched the SCOPUS database using the terms "pulmonary metastasectomy" or "lung resection" or "lung metastasectomy" or lung metastasectomies" and sarcoma and survival in the title, abstract, and keywords of all documents. Over the study period (1976-June 2021), a total of 438 documents of published articles were retrieved and 192 were identified for bibliometric analysis, and of those, 128 articles were included in the content analysis. No randomized trial was identified. 'Bradford's law' was applied to classify journals into 'zones' and 6 journals appeared to publish 70/192 (36.4%) of all articles, receiving 52% of the citations. The vast majority of articles 64% were retrospective cohort analyses. A total of 49 articles reported on prognostic factors. Pulmonary metastasectomy is frequently performed for lung metastases originating from STS. The literature continues to evolve in the form of retrospective cohort studies. It is important to review and utilize the prognostic factors to identify patients for pulmonary metastasectomy to enhance the survival outcome

Association of Vitamin D Level with Diabetic Peripheral Neuropathy

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A Literature Review on Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis and its Complications

Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are delayed-type hypersensitivity reactions to medications. Early signs of identification and proper management are critical for patients’ survival. The distinct features initially resemble influenza-like conditions, malaise, and fever with gradual pain and lesions in the oral, ocular, and genital areas along with other systemic symptoms. SJS/TEN can be differentiated: SJS by the degree of skin involvement and TEN by the degree of exfoliation. In SJS, skin involvement is 30%; overlapping among the two develops with 10–30% skin involvement. For the identification of culprit drugs, oral provocation tests, patch testing, and in vitro assay tests are used. The estimation of mortality rates for SJS/TEN has been performed by using SCORTEN- severity-of-illness score for toxic epidermal necrolysis. Sulfonamides, anti-epileptics, NSAIDs (oxicams), and allopurinol are some of the medications with a high risk of SJS/TEN development. Drug-mediated SJS/TEN is facilitated by genetic involvement particularly HLA antigens along with CYP450 genetic variants. Most frequent clinical features include mucosal involvement of nasopharyngeal, esophageal, and genital regions accompanying blisters and erosions. A multidisciplinary approach is required for the handling and treatment of SJS/TEN. It is mandatory to withdraw the contributing medicine followed by supportive therapy. Clinical management involves the use of corticosteroids, cyclosporine, and immunoglobulins

Experience of Endoscopic Ultrasound Fine Needle Aspiration in Tertiary Care Hospital

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The Aftermath of Flood Crises- Diphtheria Outbreak in Sindh

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